--- title: Spravato® Treatment Program date: 2023-01-31T22:08:09Z modified: 2026-09-10T21:33:48Z permalink: "https://www.grwhealth.com/mental-health-treatment-programs-west-virginia/spravato-treatment-program/" type: page status: publish excerpt: The first nasal spray approved by the FDA for treating adults with treatment-resistant depression. wpid: 216 featured_image: "https://www.grwhealth.com/wp-content/uploads/2025/01/Harmony-Spravato.jpeg" featured_image_alt: Young woman looking up with a hopeful expression in an urban park setting, Concept of optimism, dreams, and enjoying simple moments timestamp: 2026-09-10T21:33:48Z tags: [] --- ## Relief from Depression Symptoms Is Possible Harmony is proud to offer Spravato®, an esketamine-based nasal spray recognized for its fast-acting relief from depression symptoms, with many clients noticing improvements within hours. It works by rapidly shifting brain chemistry to ease symptoms like sadness, hopelessness, and low motivation. Complete our Spravato® form below to see if it could be the right fit for providing you with the relief you deserve. Spravato® is administered directly in our clinics under close supervision from a healthcare professional. This treatment is often effective for people who haven’t found relief through traditional antidepressants or talk therapy alone. While it’s not a cure for depression, it can provide significant symptom relief and support a meaningful improvement in quality of life for many who have lost hope after trying other treatments without improvement. Depending on your specific [insurance plan](https://www.grwhealth.com/wp-content/uploads/wp-mfa-exports/page/insurances.md), Spravato® may be covered under either your medical or pharmacy benefit. ## How Spravato® Works ![](https://nehs.transformationsnetwork.com/wp-content/uploads/2024/12/63979de8-spravato-nasal-spray_10wa0wa0wa0se000022028-1.png) Our Spravato® treatment process typically follows these steps: - **Initial evaluation and screening:** First, a clinician will determine whether Spravato® is an appropriate treatment for your depression. - **An educational session:** Our team will walk you through exactly how Spravato® works and what to expect before treatment begins. - **In-office administration:** A qualified healthcare professional administers the medication at our clinic, then monitors you for any side effects for the next two hours. - **Regular appointments:** You’ll follow an agreed-upon schedule for regular Spravato® doses in our clinics, with ongoing monitoring of your progress over time. - **Continued therapeutic support:** Your collaborative care team, including your therapist and psychiatric provider, will work with you to build individualized strategies for managing your depression symptoms. We want you to feel fully supported on your depression treatment journey. We understand how depression can make you feel stripped of your agency and motivation, so our clinicians are there with you starting from your very first screening appointment. With proper, consistent care, we believe lasting mental wellness is achievable for every client we work with. [View Full Prescribing Information.](https://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/SPRAVATO-pi.pdf) ## Spravato® Helps Every Aspect of Depression Treatment Work Better The beauty of Spravato® is that it works differently from other depression medications. It acts on glutamate, which boosts overall function and communication in the brain. This boost in neuroplasticity can help people find new insights in therapy, have an easier time implementing coping skills, better connect with the depths of their emotions, and often find their medication more effective. That’s why we recommend that Spravato® be just one part of a comprehensive depression treatment plan. ## Find out if Spravato® could help relieve your depression symptoms. [ Call Us \*DM\_DirectNumber format=period\* ](tel:304.410.0082) [ Complete the Spravato Form ](#form) ## Frequently Asked Questions Is Spravato® safe? Yes, Spravato® is considered a safe treatment for depression, with minimal side effects for most people. Our team thoroughly reviews your medical history and closely monitors for any adverse reactions during and after treatment. Does Spravato® hurt to use? Since Spravato® is delivered as a nasal spray, some mild nasal discomfort is possible during administration. Our team provides guidance and support to help make treatment sessions as comfortable as possible. How do I know if Spravato® is right for me? Spravato® tends to work well for those managing [difficult-to-treat depression](https://www.grwhealth.com/wp-content/uploads/wp-mfa-exports/post/what-is-treatment-resistant-depression.md), especially people who haven’t experienced significant relief through more traditional treatment approaches. You won’t make this decision on your own. Our providers will ask a thorough set of questions about your symptoms, history, and lifestyle to determine whether Spravato® is the right approach. Is a referral needed to get Spravato®? No, a referral isn’t required to start Spravato® treatment with us. Our team can evaluate your symptoms directly and help determine whether it makes sense for you. How quickly will I see results? Many clients report noticing relief within just a few hours to days of starting treatment, though experiences vary from person to person. If you’re not seeing results after a few doses, talk to your prescriber. Does Spravato® actually work? Spravato® has performed well in clinical trials. Following a 30-day trial period, 62% of participants reported improved social functioning and 53% reported a better overall quality of life. Additionally, 41% saw an increased ability to work, 37% reported being better able to meet basic needs, and 34% experienced improved general health.¹ Will my insurance cover Spravato®? Many insurance plans offer coverage for Spravato®, and co-pay assistance and payment plans may be available to make this treatment more accessible. Our team can help you check your coverage and understand associated costs. Yes, Spravato® is considered a safe treatment for depression, with minimal side effects for most people. Our team thoroughly reviews your medical history and closely monitors for any adverse reactions during and after treatment. Since Spravato® is delivered as a nasal spray, some mild nasal discomfort is possible during administration. Our team provides guidance and support to help make treatment sessions as comfortable as possible. Spravato® tends to work well for those managing [difficult-to-treat depression](https://www.grwhealth.com/wp-content/uploads/wp-mfa-exports/post/what-is-treatment-resistant-depression.md), especially people who haven’t experienced significant relief through more traditional treatment approaches. You won’t make this decision on your own. Our providers will ask a thorough set of questions about your symptoms, history, and lifestyle to determine whether Spravato® is the right approach. No, a referral isn’t required to start Spravato® treatment with us. Our team can evaluate your symptoms directly and help determine whether it makes sense for you. Many clients report noticing relief within just a few hours to days of starting treatment, though experiences vary from person to person. If you’re not seeing results after a few doses, talk to your prescriber. Spravato® has performed well in clinical trials. Following a 30-day trial period, 62% of participants reported improved social functioning and 53% reported a better overall quality of life. Additionally, 41% saw an increased ability to work, 37% reported being better able to meet basic needs, and 34% experienced improved general health.¹ Many insurance plans offer coverage for Spravato®, and co-pay assistance and payment plans may be available to make this treatment more accessible. Our team can help you check your coverage and understand associated costs. ## Find out if Spravato® could help relieve your depression symptoms. [ Call Us \*DM\_DirectNumber format=period\* ](tel:304.410.0082) [ Complete the Spravato Form ](#form) ![](https://www.grwhealth.com/wp-content/uploads/2025/01/Path-1003.png) ““I was hoping to at least shake the dark cloud a little bit and have a couple of days without feeling so down. But to my surprise, those days are gone. Absolutely gone.” Krista “I became interested again in the things I had set aside for over a year, such as crafting, crocheting, writing — I even started to become more present with my family and at my job.” Carol ![](https://www.grwhealth.com/wp-content/uploads/2025/01/Path-1004.png) ## Start Spravato® Treatment with Harmony If traditional depression treatments haven’t worked for you, Harmony offers Spravato® as part of a full range of mental health services, including therapy, psychiatric medication management, and other options for treatment-resistant depression. Our collaborative, multidisciplinary approach allows us to build a treatment plan tailored to your unique needs and goals. We’re passionate about helping our neighbors in Charleston, Morgantown, Wheeling, and across West Virginia get the care they deserve. Call \[Direct\] for more information, or [complete our Spravato® form](https://www.grwhealth.com/wp-content/uploads/wp-mfa-exports/page/spravato-treatment-program.md#form) to see if you or a loved one could be a good candidate for this treatment. [View Full Prescribing Information.](https://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/SPRAVATO-pi.pdf) Footnote: [Janssen Scientific Affairs – Real World Evidence – Effectiveness and Safety of SPRAVATO Therapy](https://www.janssenscience.com/products/spravato/medical-content/real-world-evidence-effectiveness-and-safety-of-spravato-therapy)